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KMID : 0383820100680060350
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Tuberculosis and Respiratory Diseases
2010 Volume.68 No. 6 p.350 ~ p.353
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The First Case of Novel Influenza A (H1N1) Fatality in Korea
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Seol Hee-Yun
Eom Jung-Seop
Kim Mi-Hyun
Cho Woo-Hyun
Kim Ji-Eun
Kim Ki-Uk
Jeon Doo-Soo
Park Hye-Kyung
Kim Yun-Seong
Lee Min-Ki
Park Soon-Kew
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Abstract
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Here we report the first fatality caused by H1N1 influenza virus infection with acute respiratory distress syndrome in Korea. A 55-year-old man presented at our emergency department with dyspnea, fever, diffuse myalgia and malaise. Bilateral lung air-space consolidation was detected on his initial chest radiograph combined with severe hypoxemia. He was supported by mechanical ventilation and treated with antibiotics. A nasopharyngeal aspirate was positive for influenza A rapid antigen and oseltamivir was started on day 3 of admission. The nasal swab sample was positive for influenza H1N1 virus by real-time reverse-transcriptase polymerase chain reaction. Despite aggressive treatment, he had refractory hypoxemia and uncontrolled septic shock. On day 5 of admission he went into cardiac arrest and expired.
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KEYWORD
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Influenza A Virus, H1N1 Subtype, Pneumonia, Viral, Respiratory Insufficiency, Death
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